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The American Journal of Pathology

In esophageal injury models, BPC-157 normalizes sphincter function by increasing pressure in both the lower esophageal sphincter (LES) and pyloric sphincter (PS) in animals with sphincter dysfunction, while in healthy animals the peptide demonstrates adaptive effects that maintain physiological sphincter tone

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The Role of SAM and SIRT1 Activation With more NAD+ available, the body can activate key cellular pathways that are often dormant during metabolic stress

Case reports Case reports highlight rare but impactful interventions for severe cases

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