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Older adults may have higher risk factors for B12 deficiency due to gastrointestinal disorders, dietary factors, or certain medications (like proton pump inhibitors or metformin) that can interfere with B12 absorption

While these findings are encouraging, it is important to recognize that the available literature remains limited

The global clinical trial program includes 2 pivotal phase 3 trials, which included approximately 4600 adults with overweight or obesity

Enhanced recovery processes in preclinical models

CGRP, the calcitonin gene-related peptide, inhibits excessive osteoclast activity while promoting osteoblast function, supporting a remodeling process that favors net bone formation

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