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The Nrf2 pathway is thus considered a key modulator of the oxidant/antioxidant balance and it has been shown that (poly)phenolic compounds could induce a response in targeted cells, leading to the activation of several defence enzymes such as glutathione-S-transferase, haem oxygenase 1, quinone oxidoreductase 1 and glutamyl-cysteine ligase (Reference Satta, Mahmoud and Wilkinson84)

Women are affected more frequently than men, with an overall female-to-male ratio of 1.8:1 (127 females, 70 males)

Beyond diabetes and obesity: GLP-1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

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