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Additionally, fasting promoted fatty acid oxidation, particularly in the liver, which contributed to the lower C3/C2 and methylcitrate/citrate ratios

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Although these findings were once controversial, there is no denying that more and more companies are now developing combined agonist drugs to achieve greater weight loss

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Adjustments to the medication regimen, dosage changes, or additional supportive treatments may be necessary

Front Pharmacol 14:1119046