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discussion 496

Data were visualized with GraphPad Prism software version 8

Does IGF-1 LR3 build muscle directly

In mice, a high-fat diet has also been shown to impair leptin signaling by attenuating STAT3 activation, thus contributing to leptin resistance [18].Leptin receptor activation engages intracellular proteins, such as protein tyrosine phosphatase1 B (PTP1B) and suppressor of cytokine signaling-3, that terminate receptor signaling

Normalized data were then exported as GraphPad files and subjected to statistical analysis using GraphPad 9.0 software

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