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Curcumin administration has been associated with beneficial changes in gut microbiota composition, leading to improved intestinal barrier function and reduced endotoxin levels that may contribute to liver inflammation through toll-like receptor (TLR) pathways

Satiety guidance remains relevant when meal portions change during treatment

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Therefore, to further assess the effect of metformin on both rectal cancer and normal, non-cancer rectal tissue, the protein secretome of treatment nave rectal tumour biopsies and non-cancer biopsies was assessed following metformin treatment

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