These aren't symptoms that should be downplayed
Bolton, Jennifer L., et al
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56 A short duration of treatment may also have prevented significant changes in HRQoL in HFrEF studies
In subjects with obesity, elevated TSH concentrations may result from stimulation of the hypothalamus-pituitary-thyroid (HPT) axis by centrally acting leptin, which activates thyrotropin-releasing hormone (TRH) neurons, leading to increased TSH and THs secretion [127]