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Some have shown partial success, and this is most likely due to NACs limited ability to increase glutathione levels [3]
Aged garlic extract the only water-based garlic supplement showed a safe profile in toxicity studies and exhibited no undesirable side effects when combined with anticoagulants (warfarin), antiplatelets (aspirin), cholesterol-lowering (statins) drugs, or anticancer drugs (doxorubicin, 5-fluorouracil, methotrexate) in clinical settings (reviewed in 6)
Although evidence from clinical trials is limited, NAC appears to be of benefit in a variety of contexts for treatment or prevention of respiratory infections, at a dose of 1200 mg per day orally (or by nasogastric tube), or as inhalation
Genes Dev (2012) 26(12):132638