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But what really sets these treatments apart is their dual-action potential

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3.3 Development of unimolecular agents targeting both GIPR and GLP-1R The anti-obesity effects of GIPR antagonism antibody, both alone and in combination with GLP-1RAs, have been demonstrated in preclinical models of mice and monkeys (68, 73)

Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom

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Varenicline is a partial agonist of the nicotinic cholinergic receptors that modulates reward processing and reduces nicotine craving [40]