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Description

List of Abbreviations: BAbile acids, BSHbile salt hydrolase, CAcholic acid, CDCAchenodeoxycholic acid, DCAdeoxycholic acid, LCAlithocholic acid, UDCAursodeoxycholic acid, UCAursodeoxycholic acid epimer (ursodeoxycholate), C24carbon-24 position of the steroid backbone, C3/C7/C12carbon positions at which oxidation, epimerization or hydroxyl modifications occur, bai operonbile acidinducible gene cluster responsible for 7-dehydroxylation, HSDHhydroxysteroid dehydrogenase (3/-HSDH, 7/-HSDH, 12/-HSDH), -OHhydroxyl group, =Oketo group, Gly/Tauglycine- and taurine-conjugated bile acids, Iso-BAiso-bile acid (epimer formed by 3- or 7-epimerization)

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Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

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Since the W/O/W method optimized drug delivery, and in vivo studies confirmed its effectiveness in glycemic control and organ protection, these advancements help address patient compliance challenges and facilitate clinical translation

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