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The resulting crude peptide is then cleaved from the resin, deprotected, and subjected to multistep purification (chromatography, crystallization) to remove byproducts, protecting groups, and residual solvent ( [20] )
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10.1016/j.cbi.2020.108968 [DOI] [PubMed] [Google Scholar] 52.Bliddal H, Bays H, Czernichow S, Udden Hemmingsson J, Hjelmesaeth J, Hoffmann Morville T, Koroleva A, Skov Neergaard J, Velez Sanchez P, Wharton S, Wizert A, Kristensen LE, Group SS (2024) Once-weekly semaglutide in persons with obesity and knee osteoarthritis
Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis
