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The gut microbiota is believed to play a role in the severity of SCD because the permeability of the intestinal barrier is compromised

Co-administration of iRGD with sorafenib-loaded iron-based metal-organic framework as a targeted ferroptosis agent for liver cancer therapy

Thus, all three of the main UA transporters may contribute to the brain concentrations of UA through their action at the blood-brain barrier, although ABCG2 is thought to have the greatest effect, probably acting to remove UA from brain to blood 45

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