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The difference in total weight loss was also striking: after about two years, the surgical patients had lost an average of 28.3% of their starting body weight, while those treated with GLP-1s lost an average of 10.3%

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This selectivity proves critical for ACI applications, where maintaining viable cell numbers remains essential for therapeutic success

Changes to insulin or oral agents might be required as the effect of GLP-1 and intraoperative glucose shifts can cause unanticipated hypoglycemia or hyperglycemia

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For instance, instead of using semaglutide base, pharmacies often use salt forms, such as semaglutide sodium or semaglutide acetate